AOD-9604 5mg

AOD-9604 is also called hGH Fragment 176-191. It’s a small peptide 16 amino acids made from one specific piece of human growth hormone (hGH): the tail end, or C-terminal region. Researchers study this piece on its own, separate from the rest of the hGH molecule.

AOD-9604 belongs to a broader group of hGH-derived fragments. These are studied for narrow, specific effects — unlike GH secretagogues (such as CJC-1295 or GHRP-6), which act on the growth hormone system as a whole.

Why Study Just This Fragment?

Full hGH does two things: it promotes growth, and it affects metabolism. AOD-9604 leaves out the part of hGH linked to growth (a segment called Trp-His-Gln-Asp) and keeps only the part linked to lipid metabolism. That’s why it’s treated as its own research compound, not just “partial hGH.”

What Researchers Study

Preclinical work on AOD-9604 focuses on:

• Lipolysis (fat breakdown) and lipid release from fat tissue

• β3-adrenergic receptor signaling

• How fat tissue regulates metabolism

• How this fragment’s structure compares to full hGH

These studies are done in cell models and animals. They tell us about biological mechanisms — not about effects in humans.

How It’s Thought to Work

In experimental models, AOD-9604 appears to trigger fat breakdown through β3-adrenergic receptors. It does this without activating the growth-related signaling that full hGH triggers. That selective action is the main reason it’s studied as its own compound.

Specifications

Want more detail? See our full AOD-9604 Research article for its research history, comparisons with full hGH, and how these studies are designed.

For laboratory research use only. Not for human or animal use. Not intended to diagnose, treat, cure, or prevent any disease.